Jayapataka Swami: Mother Saci had eight miscarriages and it looked like they were not having any child. Then Jagannath Misra performed a special sacrifice yajna to get a male child, because all the eight miscarriages were female children. So then after doing this yajna, he got Viswarupa and Lord Caitanya as his sons. So some people may not have a child. Sometimes they do ayurvedic process, or sometimes they go for test tube baby, sometimes they do some adoption, and sometimes, they just try to serve Krsna and work as a team. Haribol!